STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UO65_0168Type I restriction-modification system, specificity subunit S. (409 aa)    
Predicted Functional Partners:
UO65_0169
Type I restriction-modification system, DNA-methyltransferase subunit M.
 
 
 0.998
UO65_0511
Type I restriction-modification system, DNA-methyltransferase subunit M.
 
 
 0.992
UO65_0167
Type I restriction-modification system, restriction subunit R; Subunit R is required for both nuclease and ATPase activities, but not for modification.
 
  
 0.990
UO65_0510
Type I restriction-modification system, DNA-methyltransferase subunit M.
 
 
 0.985
UO65_4723
Type II DNA modification methyltransferase.
 
 
 0.967
UO65_0166
Putative metal-dependent hydrolase.
 
     0.952
UO65_0506
Type I restriction-modification system, restriction subunit R.
 
  
 0.877
atpF
ATP synthase F0 sector subunit b; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family.
    
 
 0.806
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.670
UO65_5902
Hypothetical protein; FIG00822893.
  
    0.505
Your Current Organism:
Actinokineospora spheciospongiae
NCBI taxonomy Id: 909613
Other names: A. spheciospongiae, Actinokineospora sp. EG49, Actinokineospora spheciospongiae Kampfer et al. 2015 emend. Nouioui et al. 2018, CCM 8480, DSM 45935, LMG 27700, LMG:27700, strain EG49
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.