STRINGSTRING
degS protein (Ewingella americana) - STRING interaction network
"degS" - Outer membrane stress sensor protease in Ewingella americana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
degSOuter membrane stress sensor protease; Protein involved in serine-type endopeptidase activity, protein binding, catalytic activity and proteolysis (332 aa)    
Predicted Functional Partners:
GEAM_1075
annotation not available (359 aa)
     
 
  0.616
GEAM_2827
Anti-sigma-E factor RseA; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic proteases finish de [...] (216 aa)
   
 
  0.599
GEAM_4004
Peptidyl-prolyl cis-trans isomerase; Protein involved in protein folding (206 aa)
   
 
  0.548
rseP
Zinc metalloprotease; Protein involved in metalloendopeptidase activity, protein binding and proteolysis (450 aa)
 
 
  0.531
GEAM_0086
Periplasmic serine endoprotease DegP-like; Protein involved in protein binding, serine-type endopeptidase activity, catalytic activity, proteolysis and response to stress; Belongs to the peptidase S1C family (455 aa)
 
       
0.526
GEAM_3231
Maltoporin; Protein involved in transport (432 aa)
       
 
  0.516
GEAM_2112
Tail-specific protease; Protein involved in protein binding, serine-type peptidase activity and proteolysis; Belongs to the peptidase S41A family (689 aa)
 
 
  0.514
GEAM_0935
annotation not available (175 aa)
     
 
  0.512
rffT
TDP-N-acetylfucosamine-lipid II N-acetylfucosaminyltransferase; Catalyzes the synthesis of Und-PP-GlcNAc-ManNAcA-Fuc4NAc (Lipid III), the third lipid-linked intermediate involved in ECA synthesis; Belongs to the glycosyltransferase 56 family (362 aa)
     
  0.510
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate (507 aa)
     
  0.510
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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