STRINGSTRING
valS protein (Ewingella americana) - STRING interaction network
"valS" - Valine--tRNA ligase in Ewingella americana
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second shell of interactors
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filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
valSValine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily (951 aa)    
Predicted Functional Partners:
GEAM_0102
DNA polymerase III chi subunit; Protein involved in DNA-directed DNA polymerase activity, DNA binding and DNA replication (154 aa)
   
   
  0.894
ileS
Isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as ’pretransfer’ editing and involves the hydrolysis of activated Val-AMP. The other activity is designated ’posttransfer’ editing and involves deacylation of mischarged Val-tRNA(Ile) (938 aa)
 
0.890
leuS
Leucine--tRNA ligase; Protein involved in ATP binding, nucleotide binding, aminoacyl-tRNA ligase activity, aminoacyl-tRNA editing activity, leucine-tRNA ligase activity, leucyl-tRNA aminoacylation and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family (860 aa)
   
0.878
cysS
Cysteine--tRNA ligase; Protein involved in ATP binding, nucleotide binding, cysteine-tRNA ligase activity, aminoacyl-tRNA ligase activity, cysteinyl-tRNA aminoacylation and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family (463 aa)
 
   
  0.870
metG
Methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (618 aa)
     
 
  0.864
pheS
Phenylalanine--tRNA ligase alpha subunit; Protein involved in ATP binding, phenylalanine-tRNA ligase activity, nucleotide binding, aminoacyl-tRNA ligase activity, tRNA binding, phenylalanyl-tRNA aminoacylation and tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily (327 aa)
   
   
  0.857
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
   
   
  0.854
thrS
Threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction- L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) (642 aa)
 
   
  0.835
argS
Arginine--tRNA ligase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, arginyl-tRNA aminoacylation and tRNA aminoacylation for protein translation (586 aa)
   
   
  0.812
hisS
Protein involved in histidine-tRNA ligase activity, ATP binding and histidyl-tRNA aminoacylation (414 aa)
 
   
  0.802
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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