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pyrB protein (Ewingella americana) - STRING interaction network
"pyrB" - Protein involved in carboxyl- or carbamoyltransferase activity, amino acid binding, aspartate carbamoyltransferase activity, pyrimidine ribonucleotide biosynthetic process, cellular amino acid metabolic process and 'de novo' pyrimidine nucleobase biosynthetic process in Ewingella americana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pyrBProtein involved in carboxyl- or carbamoyltransferase activity, amino acid binding, aspartate carbamoyltransferase activity, pyrimidine ribonucleotide biosynthetic process, cellular amino acid metabolic process and ’de novo’ pyrimidine nucleobase biosynthetic process; Belongs to the ATCase/OTCase family (311 aa)    
Predicted Functional Partners:
pyrI
Aspartate carbamoyltransferase regulatory chain; Involved in allosteric regulation of aspartate carbamoyltransferase (155 aa)
  0.999
carB
Carbamoyl-phosphate synthase large chain; Protein involved in ATP binding, catalytic activity, pyrimidine ribonucleotide biosynthetic process, metabolic process and nitrogen compound metabolic process; Belongs to the CarB family (1074 aa)
  0.999
carA
Carbamoyl-phosphate synthase small chain; Protein involved in pyrimidine ribonucleotide biosynthetic process, carbamoyl phosphate biosynthetic process and glutamine catabolic process; Belongs to the CarA family (360 aa)
  0.998
pyrF
Orotidine 5’-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5’- monophosphate (OMP) to uridine 5’-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily (242 aa)
   
   
  0.953
pyrC
Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate (349 aa)
   
 
  0.946
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1296 aa)
   
 
  0.898
argI
Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline (335 aa)
 
 
0.875
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family (432 aa)
   
 
  0.862
pyrE
Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (213 aa)
 
   
  0.859
GEAM_3777
Aspartokinase/homoserine dehydrogenase; Protein involved in NADP binding, oxidoreductase activity, oxidation-reduction process, cellular amino acid metabolic process and cellular amino acid biosynthetic process (797 aa)
 
 
  0.852
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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