STRINGSTRING
chbG protein (Ewingella americana) - STRING interaction network
"chbG" - Chitooligosaccharide deacetylase in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
chbGChitooligosaccharide deacetylase; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchit [...] (253 aa)    
Predicted Functional Partners:
GEAM_0162
Chitobiose-specific 6-phospho-beta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, catalytic activity, carbohydrate metabolic process and oxidation-reduction process (447 aa)
 
 
  0.970
chbR
Chitobiose-specific regulator; Protein involved in sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, DNA binding, negative regulation of transcription, DNA-templated, carbohydrate catabolic process and regulation of transcription, DNA-templated (253 aa)
 
   
  0.900
GEAM_0164
PTS system chitobiose-specific IIA component; Protein involved in sugar-hydrogen symporter activity, phosphoenolpyruvate-dependent sugar phosphotransferase system and transport (115 aa)
   
  0.889
chbC
Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane (452 aa)
 
   
  0.865
GEAM_0166
PTS system chitobiose-specific IIB component; Protein involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity and phosphoenolpyruvate-dependent sugar phosphotransferase system (110 aa)
 
 
  0.844
GEAM_3408
6-phospho-beta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, catalytic activity, carbohydrate metabolic process and oxidation-reduction process (435 aa)
 
 
  0.839
arnC
Undecaprenyl-phosphate 4-deoxy-4-formamido-L-arabinose transferase; Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides (326 aa)
   
        0.732
arnT
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; Belongs to the glycosyltransferase 83 family (556 aa)
   
        0.687
GEAM_0672
PTS system chitobiose-specific IIA component; Protein involved in sugar-hydrogen symporter activity, phosphoenolpyruvate-dependent sugar phosphotransferase system and transport (103 aa)
   
  0.686
GEAM_0354
PTS system diacetylchitobiose-specific IIA component; Protein involved in sugar-hydrogen symporter activity, phosphoenolpyruvate-dependent sugar phosphotransferase system and transport (116 aa)
   
  0.654
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (12%) [HD]