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chbR protein (Ewingella americana) - STRING interaction network
"chbR" - Chitobiose-specific regulator in Ewingella americana
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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chbRChitobiose-specific regulator; Protein involved in sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, DNA binding, negative regulation of transcription, DNA-templated, carbohydrate catabolic process and regulation of transcription, DNA-templated (253 aa)    
Predicted Functional Partners:
chbC
Permease IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active - transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane (452 aa)
   
  0.969
GEAM_0162
Chitobiose-specific 6-phospho-beta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, catalytic activity, carbohydrate metabolic process and oxidation-reduction process (447 aa)
   
  0.933
GEAM_0166
PTS system chitobiose-specific IIB component; Protein involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity and phosphoenolpyruvate-dependent sugar phosphotransferase system (110 aa)
   
  0.905
chbG
Chitooligosaccharide deacetylase; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho- beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchit [...] (253 aa)
 
   
  0.900
GEAM_0164
PTS system chitobiose-specific IIA component; Protein involved in sugar-hydrogen symporter activity, phosphoenolpyruvate-dependent sugar phosphotransferase system and transport (115 aa)
 
   
  0.893
GEAM_0468
Protein involved in prephenate dehydratase activity, chorismate mutase activity, chorismate metabolic process and L-phenylalanine biosynthetic process (385 aa)
       
  0.709
GEAM_3408
6-phospho-beta-glucosidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, catalytic activity, carbohydrate metabolic process and oxidation-reduction process (435 aa)
   
  0.618
ilvD
Dihydroxy-acid dehydratase; Protein involved in catalytic activity, dihydroxy-acid dehydratase activity, isoleucine biosynthetic process, valine biosynthetic process, metabolic process and branched-chain amino acid biosynthetic process; Belongs to the IlvD/Edd family (616 aa)
       
    0.566
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (440 aa)
       
    0.565
GEAM_2852
Ada family regulatory protein/methylated-DNA--protein-cysteine methyltransferase; Protein involved in catalytic activity, sequence-specific DNA binding, sequence-specific DNA binding transcription factor activity, methylated-DNA-[protein]-cysteine S-methyltransferase activity, DNA binding, zinc ion binding, methyltransferase activity, DNA repair and regulation of transcription, DNA-templated (360 aa)
 
 
  0.559
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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