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GEAM_0172 protein (Ewingella americana) - STRING interaction network
"GEAM_0172" - Protein involved in L-serine ammonia-lyase activity, 4 iron, 4 sulfur cluster binding and gluconeogenesis in Ewingella americana
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Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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GEAM_0172Protein involved in L-serine ammonia-lyase activity, 4 iron, 4 sulfur cluster binding and gluconeogenesis (455 aa)    
Predicted Functional Partners:
GEAM_0171
Protein involved in transporter activity, amino acid transport and transport (427 aa)
   
   
  0.890
GEAM_3006
Fumarate hydratase class I; Catalyzes the reversible hydration of fumarate to (S)- malate; Belongs to the class-I fumarase family (549 aa)
       
    0.816
GEAM_3777
Aspartokinase/homoserine dehydrogenase; Protein involved in NADP binding, oxidoreductase activity, oxidation-reduction process, cellular amino acid metabolic process and cellular amino acid biosynthetic process (797 aa)
       
  0.776
GEAM_0210
Aspartokinase/homoserine dehydrogenase; Protein involved in NADP binding, oxidoreductase activity, aspartate kinase activity, cellular amino acid biosynthetic process, oxidation-reduction process and cellular amino acid metabolic process (819 aa)
       
  0.776
trpF
Multifunctional fusion protein; Protein involved in phosphoribosylanthranilate isomerase activity, indole-3-glycerol-phosphate synthase activity, catalytic activity, tryptophan metabolic process and metabolic process; Belongs to the TrpC family (454 aa)
         
  0.766
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family (957 aa)
       
  0.743
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (417 aa)
   
 
  0.722
GEAM_3120
annotation not available (324 aa)
   
  0.711
ilvA
L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (514 aa)
   
  0.707
nifJ
Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (1177 aa)
   
 
  0.684
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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