STRINGSTRING
deoA protein (Ewingella americana) - STRING interaction network
"deoA" - Thymidine phosphorylase in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
deoAThymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis; Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family (439 aa)    
Predicted Functional Partners:
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family (407 aa)
 
 
  0.990
deoC
Deoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily (259 aa)
 
 
  0.960
deoD
Protein involved in catalytic activity, purine-nucleoside phosphorylase activity, purine nucleobase salvage, nucleoside metabolic process and nucleobase-containing compound metabolic process (239 aa)
 
 
  0.946
cdd
Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2’-deoxycytidine for UMP synthesis (294 aa)
 
 
  0.907
GEAM_3069
Putative phosphopentomutase; Protein involved in metal ion binding, catalytic activity and metabolic process (418 aa)
 
 
  0.875
tdk
Thymidine kinase; Protein involved in ATP binding and thymidine kinase activity (200 aa)
 
   
  0.871
upp
Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (208 aa)
   
 
  0.870
GEAM_1024
NapF family periplasmic nitrate reductase ferredoxin-type component; Protein involved in iron-sulfur cluster binding, electron carrier activity, iron ion binding and (OBSOLETE) electron transport (186 aa)
       
    0.814
cpdB
Protein involved in hydrolase activity, 2’,3’-cyclic-nucleotide 2’-phosphodiesterase activity, nucleobase-containing compound metabolic process, nucleotide catabolic process and nucleotide metabolic process; Belongs to the 5’-nucleotidase family (653 aa)
 
   
  0.796
udp
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis; Belongs to the PNP/UDP phosphorylase family (253 aa)
     
 
  0.788
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (10%) [HD]