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folK protein (Ewingella americana) - STRING interaction network
"folK" - Protein involved in 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity and folic acid-containing compound biosynthetic process in Ewingella americana
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second shell of interactors
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proteins of unknown 3D structure
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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folKProtein involved in 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity and folic acid-containing compound biosynthetic process (159 aa)    
Predicted Functional Partners:
folP
Protein involved in dihydropteroate synthase activity, folic acid-containing compound biosynthetic process, pteridine-containing compound metabolic process and cellular metabolic process (261 aa)
 
  0.997
folB
7,8-dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin (118 aa)
 
 
  0.950
pcnB
Poly(A) polymerase I; Adds poly(A) tail to the 3’ end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control (576 aa)
 
   
  0.950
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate; Belongs to the PanB family (264 aa)
   
  0.938
folE
Protein involved in GTP cyclohydrolase I activity, pteridine-containing compound biosynthetic process and tetrahydrofolate biosynthetic process (221 aa)
   
  0.928
GEAM_0468
Protein involved in prephenate dehydratase activity, chorismate mutase activity, chorismate metabolic process and L-phenylalanine biosynthetic process (385 aa)
            0.827
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Protein involved in methionine synthase activity, cobalamin binding, metal ion binding, homocysteine S-methyltransferase activity, zinc ion binding, pteridine-containing compound metabolic process, methionine biosynthetic process and cellular metabolic process (1239 aa)
         
  0.819
folC
Dihydrofolate synthase/folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives (423 aa)
 
 
  0.802
acpS
Holo-[acyl-carrier-protein] synthase; Transfers the 4’-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family (126 aa)
            0.793
GEAM_3510
Dihydrofolate synthase/folylpolyglutamate synthase; Functions in two distinct reactions of the de novo folate biosynthetic pathway. Catalyzes the addition of a glutamate residue to dihydropteroate (7,8-dihydropteroate or H2Pte) to form dihydrofolate (7,8-dihydrofolate monoglutamate or H2Pte-Glu). Also catalyzes successive additions of L-glutamate to tetrahydrofolate or 10-formyltetrahydrofolate or 5,10-methylenetetrahydrofolate, leading to folylpolyglutamate derivatives (421 aa)
 
  0.761
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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