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pcnB protein (Ewingella americana) - STRING interaction network
"pcnB" - Poly(A) polymerase I in Ewingella americana
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pcnBPoly(A) polymerase I; Adds poly(A) tail to the 3’ end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control (576 aa)    
Predicted Functional Partners:
folK
Protein involved in 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity and folic acid-containing compound biosynthetic process (159 aa)
 
   
  0.950
rne
Ribonuclease E; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs; Belongs to the RNase E/G family. RNase E subfamily (1105 aa)
 
  0.947
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3’- to 5’-direction (706 aa)
     
  0.924
gluQ
Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (304 aa)
 
        0.924
rnr
Ribonuclease R; 3’-5’ exoribonuclease that releases 5’-nucleoside monophosphates and is involved in maturation of structured RNAs; Belongs to the RNR ribonuclease family. RNase R subfamily (847 aa)
 
  0.922
dksA
RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (120 aa)
          0.910
hfq
RNA-binding protein Hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (103 aa)
       
 
  0.826
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
   
 
    0.816
rnt
Ribonuclease T; Trims short 3’ overhangs of a variety of RNA species, leaving a one or two nucleotide 3’ overhang. Responsible for the end-turnover of tRNA- specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis (237 aa)
 
 
  0.811
GEAM_0042
Cytoplasmic axial filament protein/ribonuclease G; Protein involved in RNA binding, ribonuclease activity, RNA catabolic process and RNA processing (489 aa)
   
  0.809
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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