STRINGSTRING
sfsA protein (Ewingella americana) - STRING interaction network
"sfsA" - Sugar fermentation stimulation protein homolog in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sfsASugar fermentation stimulation protein homolog; Protein involved in maltose metabolic process; Belongs to the SfsA family (239 aa)    
Predicted Functional Partners:
GEAM_0333
RNA 2’,3’-cyclic phosphodiesterase; Hydrolyzes RNA 2’,3’-cyclic phosphodiester to an RNA 2’- phosphomonoester (181 aa)
   
   
  0.882
mutY
A/G-specific adenine glycosylase; Protein involved in 4 iron, 4 sulfur cluster binding, endonuclease activity, DNA binding, DNA N-glycosylase activity, hydrolase activity, catalytic activity, DNA replication, DNA repair, DNA recombination and base-excision repair (360 aa)
 
        0.755
hrpB
Protein involved in ATP-dependent helicase activity, ATP binding, nucleic acid binding, helicase activity and nucleobase-containing compound metabolic process (813 aa)
   
        0.692
dksA
RNA polymerase-binding transcription factor DksA; Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters. Also required for regulation of fis expression (120 aa)
   
   
  0.614
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1296 aa)
         
  0.592
gluQ
Glutamyl-Q tRNA(Asp) synthetase; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (304 aa)
   
   
  0.579
recB
RecBCD enzyme subunit RecB; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3’ direction. Cuts ssDNA a few nucleotides 3’ to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3’-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holo [...] (1194 aa)
           
  0.513
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
         
  0.500
GEAM_2226
Cytochrome b561; Protein involved in biological_process and respiratory electron transport chain (185 aa)
           
  0.457
GEAM_0110
annotation not available (122 aa)
           
  0.437
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (21%) [HD]