STRINGSTRING
rnhA protein (Ewingella americana) - STRING interaction network
"rnhA" - Ribonuclease H in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnhARibonuclease H; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (155 aa)    
Predicted Functional Partners:
dnaQ
DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3’-5’ exonuclease (232 aa)
 
 
  0.975
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (934 aa)
 
  0.969
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3’ to 5’ exonuclease activity (625 aa)
 
    0.864
dnaE
DNA-directed DNA polymerase; Protein involved in catalytic activity, nucleic acid binding, 3’-5’ exonuclease activity, DNA-directed DNA polymerase activity, DNA binding and DNA replication (1134 aa)
   
 
  0.758
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline (273 aa)
            0.750
GEAM_1681
Protein involved in biological_process (126 aa)
 
            0.730
nadD
Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (221 aa)
 
 
        0.729
rnhB
Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (197 aa)
   
 
  0.706
GEAM_4211
Protein involved in N-acetyltransferase activity (155 aa)
            0.702
hemL
Glutamate-1-semialdehyde 2,1-aminomutase; Protein involved in pyridoxal phosphate binding, transaminase activity, glutamate-1-semialdehyde 2,1-aminomutase activity, porphyrin-containing compound biosynthetic process and tetrapyrrole biosynthetic process (426 aa)
            0.688
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (12%) [HD]