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gpt protein (Ewingella americana) - STRING interaction network
"gpt" - Xanthine phosphoribosyltransferase in Ewingella americana
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
gptXanthine phosphoribosyltransferase; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily (152 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (183 aa)
   
  0.942
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
   
 
    0.885
hpt
Protein involved in hypoxanthine phosphoribosyltransferase activity, purine ribonucleoside salvage and nucleoside metabolic process; Belongs to the purine/pyrimidine phosphoribosyltransferase family (178 aa)
   
 
  0.880
deoD
Protein involved in catalytic activity, purine-nucleoside phosphorylase activity, purine nucleobase salvage, nucleoside metabolic process and nucleobase-containing compound metabolic process (239 aa)
       
  0.871
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (440 aa)
   
 
    0.868
add
Protein involved in deaminase activity, purine-containing compound salvage and purine ribonucleoside monophosphate biosynthetic process (332 aa)
   
  0.850
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (347 aa)
   
 
  0.847
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP (207 aa)
   
  0.816
GEAM_0358
annotation not available (268 aa)
 
 
    0.795
GEAM_2545
annotation not available (315 aa)
       
  0.766
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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