STRINGSTRING
hmp protein (Ewingella americana) - STRING interaction network
"hmp" - Flavohemoprotein in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hmpFlavohemoprotein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family (396 aa)    
Predicted Functional Partners:
GEAM_3268
Flavohemoprotein; Protein involved in FMN binding, pyridoxamine-phosphate oxidase activity and oxidation-reduction process (309 aa)
          0.933
GEAM_3599
Protein involved in molybdenum ion binding, pyridoxal phosphate binding and catalytic activity (226 aa)
     
  0.929
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O (550 aa)
   
 
  0.825
GEAM_0096
Aerobic respiration control sensor protein; Protein involved in phosphorelay sensor kinase activity, phosphorelay response regulator activity, signal transducer activity, ATP binding, signal transduction, regulation of transcription, DNA-templated and phosphorelay signal transduction system (779 aa)
   
 
  0.824
GEAM_1408
Signal transduction histidine kinase; Protein involved in signal transducer activity, phosphorelay sensor kinase activity, protein histidine kinase activity, ATP binding, signal transduction, chemotaxis and phosphorelay signal transduction system (675 aa)
       
  0.813
argH
Protein involved in argininosuccinate lyase activity, catalytic activity and arginine biosynthetic process via ornithine (458 aa)
         
  0.801
nirB
Nitrite reductase [NAD(P)H] large subunit; Protein involved in heme binding, oxidoreductase activity, iron-sulfur cluster binding, flavin adenine dinucleotide binding, nitrite reductase [NAD(P)H] activity, NADP binding, oxidation-reduction process and nitrate assimilation; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family (850 aa)
 
   
  0.801
nsrR
HTH-type transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity (141 aa)
 
   
  0.796
GEAM_1310
annotation not available (74 aa)
 
   
  0.784
GEAM_1119
CheV family chemotaxis protein; Protein involved in phosphorelay response regulator activity, signal transducer activity, phosphorelay signal transduction system, regulation of transcription, DNA-templated, signal transduction and chemotaxis (325 aa)
       
    0.783
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (11%) [HD]