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guaA protein (Ewingella americana) - STRING interaction network
"guaA" - GMP synthase [glutamine-hydrolyzing] in Ewingella americana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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guaAGMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)    
Predicted Functional Partners:
guaB
Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth; Belongs to the IMPDH/GMPR family (440 aa)
 
  0.999
guaC
GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides (347 aa)
   
  0.998
GEAM_0309
Arabinose 5-phosphate isomerase; Protein involved in protein binding, carbohydrate binding, isomerase activity and carbohydrate metabolic process (321 aa)
   
  0.994
GEAM_0076
Arabinose 5-phosphate isomerase; Protein involved in protein binding, carbohydrate binding, isomerase activity and carbohydrate metabolic process (328 aa)
   
  0.994
GEAM_1552
Protein involved in voltage-gated chloride channel activity, ion channel activity, biological_process, chloride transport and transmembrane transport (565 aa)
   
  0.993
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (183 aa)
   
  0.990
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate (1296 aa)
 
   
  0.988
purD
Protein involved in phosphoribosylamine-glycine ligase activity, ’de novo’ IMP biosynthetic process, purine ribonucleotide biosynthetic process and purine nucleobase biosynthetic process; Belongs to the GARS family (429 aa)
 
   
  0.978
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP (243 aa)
     
 
  0.968
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family (505 aa)
 
   
  0.965
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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