node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GEAM_0790 | GEAM_3970 | GEAM_0790 | GEAM_3970 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.916 |
GEAM_0790 | nifJ | GEAM_0790 | GEAM_1724 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, electron carrier activity, iron-sulfur cluster binding, thiamine pyrophosphate binding, catalytic activity, oxidoreductase activity, iron ion binding, oxidation-reduction process, electron transport chain and metabolic process. | 0.979 |
GEAM_0790 | nuoD | GEAM_0790 | GEAM_2402 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | NADH-ubiquinone oxidoreductase chain C/NADH-ubiquinone oxidoreductase chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.998 |
GEAM_0790 | sdhA | GEAM_0790 | GEAM_0789 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinate dehydrogenase flavoprotein subunit; Protein involved in oxidoreductase activity, oxidoreductase activity, acting on the CH-CH group of donors, flavin adenine dinucleotide binding, oxidation-reduction process, tricarboxylic acid cycle and electron transport chain; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.999 |
GEAM_0790 | sdhC | GEAM_0790 | GEAM_0787 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinate dehydrogenase cytochrome b556 subunit; Protein involved in oxidoreductase activity, acting on the CH-CH group of donors, succinate dehydrogenase activity and tricarboxylic acid cycle. | 0.999 |
GEAM_0790 | sdhD | GEAM_0790 | GEAM_0788 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.999 |
GEAM_0790 | sucA | GEAM_0790 | GEAM_0791 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 2-oxoglutarate dehydrogenase E1 component; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, oxoglutarate dehydrogenase (succinyl-transferring) activity, thiamine pyrophosphate binding, tricarboxylic acid cycle, lysine catabolic process, tryptophan metabolic process, metabolic process and oxidation-reduction process. | 0.911 |
GEAM_0790 | sucB | GEAM_0790 | GEAM_0792 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.721 |
GEAM_0790 | sucC | GEAM_0790 | GEAM_0793 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.996 |
GEAM_0790 | sucD | GEAM_0790 | GEAM_0794 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.995 |
GEAM_3970 | GEAM_0790 | GEAM_3970 | GEAM_0790 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 0.916 |
GEAM_3970 | nifJ | GEAM_3970 | GEAM_1724 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, electron carrier activity, iron-sulfur cluster binding, thiamine pyrophosphate binding, catalytic activity, oxidoreductase activity, iron ion binding, oxidation-reduction process, electron transport chain and metabolic process. | 0.979 |
GEAM_3970 | nuoD | GEAM_3970 | GEAM_2402 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | NADH-ubiquinone oxidoreductase chain C/NADH-ubiquinone oxidoreductase chain D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. | 0.998 |
GEAM_3970 | sdhA | GEAM_3970 | GEAM_0789 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinate dehydrogenase flavoprotein subunit; Protein involved in oxidoreductase activity, oxidoreductase activity, acting on the CH-CH group of donors, flavin adenine dinucleotide binding, oxidation-reduction process, tricarboxylic acid cycle and electron transport chain; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. | 0.998 |
GEAM_3970 | sdhC | GEAM_3970 | GEAM_0787 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinate dehydrogenase cytochrome b556 subunit; Protein involved in oxidoreductase activity, acting on the CH-CH group of donors, succinate dehydrogenase activity and tricarboxylic acid cycle. | 0.997 |
GEAM_3970 | sdhD | GEAM_3970 | GEAM_0788 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Succinate dehydrogenase hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH). | 0.993 |
GEAM_3970 | sucA | GEAM_3970 | GEAM_0791 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | 2-oxoglutarate dehydrogenase E1 component; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, oxoglutarate dehydrogenase (succinyl-transferring) activity, thiamine pyrophosphate binding, tricarboxylic acid cycle, lysine catabolic process, tryptophan metabolic process, metabolic process and oxidation-reduction process. | 0.763 |
GEAM_3970 | sucB | GEAM_3970 | GEAM_0792 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.575 |
GEAM_3970 | sucC | GEAM_3970 | GEAM_0793 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA ligase [ADP-forming] beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.984 |
GEAM_3970 | sucD | GEAM_3970 | GEAM_0794 | Protein involved in iron-sulfur cluster binding, electron carrier activity, oxidoreductase activity, tricarboxylic acid cycle, aerobic respiration, anaerobic respiration and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. | succinyl-CoA ligase [ADP-forming] alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.982 |