STRINGSTRING
gpmA protein (Ewingella americana) - STRING interaction network
"gpmA" - 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily (250 aa)    
Predicted Functional Partners:
eno
Enolase; Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (431 aa)
   
  0.982
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family (255 aa)
 
  0.976
pgk
Protein involved in phosphoglycerate kinase activity and glycolysis; Belongs to the phosphoglycerate kinase family (387 aa)
     
  0.972
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family (792 aa)
   
 
  0.950
pgi
Protein involved in glucose-6-phosphate isomerase activity, gluconeogenesis and glycolysis; Belongs to the GPI family (548 aa)
     
 
  0.949
galK
Galactokinase; Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P); Belongs to the GHMP kinase family. GalK subfamily (383 aa)
       
  0.889
gpmB
annotation not available (215 aa)
 
  0.882
fbaA
Fructose-bisphosphate aldolase class II; Protein involved in aldehyde-lyase activity, zinc ion binding, fructose-bisphosphate aldolase activity, glycolysis and carbohydrate metabolic process (359 aa)
     
  0.879
GEAM_1866
Tagatose 1,6-bisphosphate aldolase; Protein involved in aldehyde-lyase activity, zinc ion binding, tagatose-bisphosphate aldolase activity and carbohydrate metabolic process (292 aa)
     
  0.879
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone (491 aa)
     
  0.875
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (14%) [HD]