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msbA protein (Ewingella americana) - STRING interaction network
"msbA" - Lipid A export ATP-binding/permease protein MsbA in Ewingella americana
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query proteins and first shell of interactors
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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msbALipid A export ATP-binding/permease protein MsbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation; Belongs to the ABC transporter superfamily. Lipid exporter (TC 3.A.1.106) family (581 aa)    
Predicted Functional Partners:
GEAM_1035
Metallo-beta-lactamase superfamily hydrolase; Protein involved in hydrolase activity, DNA import into cell involved in transformation and establishment of competence for transformation (753 aa)
       
  0.827
lpxK
Tetraacyldisaccharide 4’-kinase; Transfers the gamma-phosphate of ATP to the 4’-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4’-bis-phosphate (lipid IVA) (278 aa)
        0.742
dnaK
Chaperone protein DnaK; Acts as a chaperone (633 aa)
   
 
  0.533
GEAM_0100
Putative permease; FIG000988; overlaps another CDS with the same product name; Protein involved in biological_process (364 aa)
 
    0.526
ihfB
Integration host factor subunit beta; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (94 aa)
 
        0.483
lpxD
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily (340 aa)
 
      0.471
GEAM_0076
Arabinose 5-phosphate isomerase; Protein involved in protein binding, carbohydrate binding, isomerase activity and carbohydrate metabolic process (328 aa)
 
    0.460
lpdA
Dihydrolipoyl dehydrogenase; Protein involved in flavin adenine dinucleotide binding, oxidoreductase activity, dihydrolipoyl dehydrogenase activity, glycolysis, cell redox homeostasis, dihydrolipoamide metabolic process and oxidation-reduction process (474 aa)
   
      0.459
GEAM_0099
Putative permease; FIG000906; overlaps another CDS with the same product name; Protein involved in biological_process (356 aa)
 
 
    0.457
leuS
Leucine--tRNA ligase; Protein involved in ATP binding, nucleotide binding, aminoacyl-tRNA ligase activity, aminoacyl-tRNA editing activity, leucine-tRNA ligase activity, leucyl-tRNA aminoacylation and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family (860 aa)
   
      0.441
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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