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fabA protein (Ewingella americana) - STRING interaction network
"fabA" - 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase in Ewingella americana
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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fabA3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16-0, being most active on intermediate chain length (172 aa)    
Predicted Functional Partners:
GEAM_2448
3-oxoacyl-[acyl-carrier-protein] synthase, KASI; Protein involved in catalytic activity and metabolic process; Belongs to the beta-ketoacyl-ACP synthases family (406 aa)
  0.933
acpP
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis (78 aa)
   
  0.933
fabG
Protein involved in oxidoreductase activity, NAD binding, 3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity, fatty acid biosynthetic process, metabolic process and oxidation-reduction process (244 aa)
     
  0.919
fabZ
3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (171 aa)
     
 
  0.909
fabV
Enoyl-[acyl-carrier-protein] reductase [NADH]; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family (399 aa)
   
 
  0.894
GEAM_3273
Short-chain dehydrogenase/reductase family oxidoreductase; Protein involved in oxidoreductase activity and metabolic process (252 aa)
     
  0.886
GEAM_0489
Protein involved in oxidoreductase activity and metabolic process (243 aa)
     
  0.847
GEAM_1424
annotation not available (178 aa)
     
  0.828
fabD
Protein involved in [acyl-carrier-protein] S-malonyltransferase activity, catalytic activity, protein binding, fatty acid biosynthetic process and metabolic process (310 aa)
 
  0.819
GEAM_3714
3-oxoacyl-[acyl-carrier-protein] synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (424 aa)
 
  0.813
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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