STRINGSTRING
GEAM_1299 protein (Ewingella americana) - STRING interaction network
"GEAM_1299" - Alcohol dehydrogenase in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GEAM_1299Alcohol dehydrogenase; Protein involved in oxidoreductase activity, zinc ion binding, transferase activity, transferring acyl groups other than amino-acyl groups and oxidation-reduction process (343 aa)    
Predicted Functional Partners:
GEAM_1982
Aldehyde-alcohol dehydrogenase; Protein involved in oxidoreductase activity, metal ion binding, oxidation-reduction process and metabolic process; In the C-terminal section; belongs to the iron- containing alcohol dehydrogenase family (891 aa)
   
  0.929
GEAM_0978
S-(hydroxymethyl)glutathione dehydrogenase; Protein involved in oxidoreductase activity, zinc ion binding, S-(hydroxymethyl)glutathione dehydrogenase activity, transferase activity, transferring acyl groups other than amino-acyl groups, fermentation, toxin metabolic process, oxidation-reduction process and ethanol oxidation; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily (374 aa)
 
0.876
GEAM_2681
Monoamine oxidase; Protein involved in oxidoreductase activity and oxidation-reduction process (374 aa)
       
    0.814
GEAM_0548
Aldehyde dehydrogenase; Protein involved in oxidoreductase activity, aldehyde dehydrogenase [NAD(P)+] activity, oxidation-reduction process, metabolic process and cellular aldehyde metabolic process; Belongs to the aldehyde dehydrogenase family (436 aa)
   
  0.800
GEAM_2508
Pyruvate/alpha-keto-acid decarboxylase; Protein involved in magnesium ion binding, thiamine pyrophosphate binding and catalytic activity; Belongs to the TPP enzyme family (552 aa)
 
 
 
  0.789
astD
N-succinylglutamate 5-semialdehyde dehydrogenase; Catalyzes the NAD-dependent reduction of succinylglutamate semialdehyde into succinylglutamate (492 aa)
   
  0.780
GEAM_0036
Alcohol dehydrogenase; Protein involved in oxidoreductase activity, zinc ion binding, transferase activity, transferring acyl groups other than amino-acyl groups, metabolic process and oxidation-reduction process (325 aa)
     
 
  0.765
GEAM_2933
annotation not available (454 aa)
     
 
    0.761
fadB
Fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long-chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate; In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family (726 aa)
   
 
  0.708
fadJ
Fatty acid oxidation complex subunit alpha; Catalyzes the formation of a hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities; In the central section; belongs to the 3-hydroxyacyl- CoA dehydrogenase family (716 aa)
   
 
  0.708
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (11%) [HD]