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GEAM_1306 protein (Ewingella americana) - STRING interaction network
"GEAM_1306" - Protein involved in DNA-directed DNA polymerase activity, damaged DNA binding and DNA repair in Ewingella americana
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
GEAM_1306Protein involved in DNA-directed DNA polymerase activity, damaged DNA binding and DNA repair (420 aa)    
Predicted Functional Partners:
GEAM_1307
annotation not available (80 aa)
 
  0.988
GEAM_4241
annotation not available (140 aa)
 
  0.981
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (934 aa)
   
  0.793
lexA
LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5’-CTGTATATATATACAG-3’. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (202 aa)
 
  0.720
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (354 aa)
   
  0.686
dnaN
Beta sliding clamp; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3’-5’ exonuclease proofreading activity. The beta chain is required for initiation of replication as [...] (366 aa)
     
  0.644
nifJ
Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (1177 aa)
     
 
  0.642
GEAM_0249
Protein involved in DNA-directed DNA polymerase activity, nucleotide binding, DNA binding, nucleic acid binding, DNA replication and nucleobase-containing compound metabolic process (766 aa)
     
  0.640
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (548 aa)
       
 
  0.527
nusA
Transcription termination/antitermination protein NusA; Participates in both transcription termination and antitermination (495 aa)
       
 
  0.500
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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