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alsS protein (Ewingella americana) - STRING interaction network
"alsS" - Acetolactate synthase, catabolic in Ewingella americana
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Predicted Interactions
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textmining
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protein homology
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alsSAcetolactate synthase, catabolic; Protein involved in magnesium ion binding, thiamine pyrophosphate binding, catalytic activity, acetolactate synthase activity, fermentation, acetoin biosynthetic process and butanediol metabolic process; Belongs to the TPP enzyme family (558 aa)    
Predicted Functional Partners:
budA
Protein involved in acetolactate decarboxylase activity, fermentation, acetoin biosynthetic process and polyol metabolic process (267 aa)
 
   
  0.993
nifJ
Pyruvate-flavodoxin oxidoreductase; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin (1177 aa)
 
  0.949
GEAM_0264
Protein involved in acetolactate synthase activity, isoleucine biosynthetic process, valine biosynthetic process and branched-chain amino acid biosynthetic process (163 aa)
 
  0.916
ilvC
Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate; Belongs to the ketol-acid reductoisomerase family (491 aa)
   
 
  0.870
leuB
3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (365 aa)
  0.862
uca
Urea carboxylase; Protein involved in ligase activity, ATP binding, catalytic activity, peptidyl-prolyl cis-trans isomerase activity, urea metabolic process, metabolic process and protein folding (1212 aa)
   
 
    0.826
GEAM_2546
NADP-dependent malic enzyme; Protein involved in NAD binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, transferase activity, transferring acyl groups, oxidation-reduction process and metabolic process (759 aa)
   
 
  0.822
GEAM_3799
annotation not available (87 aa)
   
  0.821
ilvA
L-threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA (514 aa)
   
  0.811
GEAM_3120
annotation not available (324 aa)
   
  0.811
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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