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GEAM_1338 protein (Ewingella americana) - STRING interaction network
"GEAM_1338" - ATP-dependent Clp protease proteolytic subunit in Ewingella americana
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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GEAM_1338ATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins; Belongs to the peptidase S14 family (204 aa)    
Predicted Functional Partners:
clpX
ATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (424 aa)
  0.967
groL
60 kDa chaperonin; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (548 aa)
 
 
  0.798
GEAM_1340
ArsR family transcriptional regulator; Protein involved in sequence-specific DNA binding transcription factor activity and regulation of transcription, DNA-templated (103 aa)
              0.790
GEAM_1339
Protein involved in biological_process (109 aa)
              0.790
groS
10 kDa chaperonin; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (97 aa)
 
 
  0.688
GEAM_1342
4-carboxymuconolactone decarboxylase; Protein involved in peroxiredoxin activity and oxidation-reduction process (100 aa)
              0.665
GEAM_1341
annotation not available (127 aa)
              0.665
lon
Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (784 aa)
 
 
  0.656
clpA
ATP-dependent Clp protease ATP-binding subunit; Protein involved in ATP binding, ATP-dependent peptidase activity, nucleotide binding, nucleoside-triphosphatase activity, (OBSOLETE) ATP-dependent proteolysis, protein unfolding and protein metabolic process; Belongs to the ClpA/ClpB family (736 aa)
     
 
  0.647
nuoI
NADH-quinone oxidoreductase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (180 aa)
   
   
  0.638
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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