STRINGSTRING
metG protein (Ewingella americana) - STRING interaction network
"metG" - Methionine--tRNA ligase in Ewingella americana
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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metGMethionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (618 aa)    
Predicted Functional Partners:
pheS
Phenylalanine--tRNA ligase alpha subunit; Protein involved in ATP binding, phenylalanine-tRNA ligase activity, nucleotide binding, aminoacyl-tRNA ligase activity, tRNA binding, phenylalanyl-tRNA aminoacylation and tRNA aminoacylation; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily (327 aa)
   
  0.975
pheT
Phenylalanine--tRNA ligase beta subunit; Protein involved in tRNA binding, RNA binding, ATP binding, magnesium ion binding, phenylalanine-tRNA ligase activity, nucleotide binding, phenylalanyl-tRNA aminoacylation and tRNA processing; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily (795 aa)
   
 
  0.974
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Protein involved in methionine synthase activity, cobalamin binding, metal ion binding, homocysteine S-methyltransferase activity, zinc ion binding, pteridine-containing compound metabolic process, methionine biosynthetic process and cellular metabolic process (1239 aa)
     
 
  0.942
argS
Arginine--tRNA ligase; Protein involved in nucleotide binding, arginine-tRNA ligase activity, ATP binding, aminoacyl-tRNA ligase activity, arginyl-tRNA aminoacylation and tRNA aminoacylation for protein translation (586 aa)
   
  0.940
leuS
Leucine--tRNA ligase; Protein involved in ATP binding, nucleotide binding, aminoacyl-tRNA ligase activity, aminoacyl-tRNA editing activity, leucine-tRNA ligase activity, leucyl-tRNA aminoacylation and tRNA aminoacylation for protein translation; Belongs to the class-I aminoacyl-tRNA synthetase family (860 aa)
   
  0.932
lysS
Lysine--tRNA ligase; Protein involved in nucleic acid binding, ATP binding, nucleotide binding, aminoacyl-tRNA ligase activity, lysine-tRNA ligase activity, lysyl-tRNA aminoacylation and tRNA aminoacylation for protein translation; Belongs to the class-II aminoacyl-tRNA synthetase family (514 aa)
 
  0.924
arnA
Bifunctional polymyxin resistance protein ArnA; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP-L-Ara4N formyltransferase subfamily (660 aa)
   
 
  0.924
proS
Proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction- proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as ’pretransfer’ editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated ’posttransfer’ editing and involves deacy [...] (572 aa)
   
  0.915
fmt
Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus (311 aa)
   
 
  0.914
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (525 aa)
   
 
  0.910
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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