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hisC protein (Ewingella americana) - STRING interaction network
"hisC" - Protein involved in pyridoxal phosphate binding, histidinol-phosphate transaminase activity, histidine biosynthetic process and biosynthetic process in Ewingella americana
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisCProtein involved in pyridoxal phosphate binding, histidinol-phosphate transaminase activity, histidine biosynthetic process and biosynthetic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (378 aa)    
Predicted Functional Partners:
hisE
Histidine biosynthesis bifunctional protein HisIE; Protein involved in phosphoribosyl-AMP cyclohydrolase activity, phosphoribosyl-ATP diphosphatase activity and histidine biosynthetic process; In the N-terminal section; belongs to the PRA-CH family (213 aa)
 
  0.999
hisB
Histidine biosynthesis bifunctional protein HisB; Protein involved in imidazoleglycerol-phosphate dehydratase activity, histidinol-phosphatase activity, phosphatase activity and histidine biosynthetic process (360 aa)
 
  0.999
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (438 aa)
  0.999
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (257 aa)
  0.999
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Protein involved in 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase activity, catalytic activity, histidine biosynthetic process and metabolic process (245 aa)
   
  0.998
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (196 aa)
 
 
  0.998
hisG
Protein involved in ATP phosphoribosyltransferase activity, magnesium ion binding and histidine biosynthetic process (289 aa)
 
 
  0.998
tyrA
T-protein; Protein involved in prephenate dehydrogenase (NADP+) activity, prephenate dehydrogenase activity, chorismate mutase activity, chorismate metabolic process, oxidation-reduction process and tyrosine biosynthetic process (373 aa)
 
  0.976
GEAM_0468
Protein involved in prephenate dehydratase activity, chorismate mutase activity, chorismate metabolic process and L-phenylalanine biosynthetic process (385 aa)
 
  0.971
GEAM_3777
Aspartokinase/homoserine dehydrogenase; Protein involved in NADP binding, oxidoreductase activity, oxidation-reduction process, cellular amino acid metabolic process and cellular amino acid biosynthetic process (797 aa)
 
 
  0.934
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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