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hisD protein (Ewingella americana) - STRING interaction network
"hisD" - Histidinol dehydrogenase in Ewingella americana
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (438 aa)    
Predicted Functional Partners:
hisE
Histidine biosynthesis bifunctional protein HisIE; Protein involved in phosphoribosyl-AMP cyclohydrolase activity, phosphoribosyl-ATP diphosphatase activity and histidine biosynthetic process; In the N-terminal section; belongs to the PRA-CH family (213 aa)
 
  0.999
hisB
Histidine biosynthesis bifunctional protein HisB; Protein involved in imidazoleglycerol-phosphate dehydratase activity, histidinol-phosphatase activity, phosphatase activity and histidine biosynthetic process (360 aa)
  0.999
hisC
Protein involved in pyridoxal phosphate binding, histidinol-phosphate transaminase activity, histidine biosynthetic process and biosynthetic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (378 aa)
  0.999
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (196 aa)
 
  0.999
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (257 aa)
  0.999
hisG
Protein involved in ATP phosphoribosyltransferase activity, magnesium ion binding and histidine biosynthetic process (289 aa)
 
  0.998
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Protein involved in 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase activity, catalytic activity, histidine biosynthetic process and metabolic process (245 aa)
 
  0.998
gmhB
D,D-heptose 1,7-bisphosphate phosphatase; Protein involved in phosphatase activity and carbohydrate metabolic process (188 aa)
   
  0.884
trpF
Multifunctional fusion protein; Protein involved in phosphoribosylanthranilate isomerase activity, indole-3-glycerol-phosphate synthase activity, catalytic activity, tryptophan metabolic process and metabolic process; Belongs to the TrpC family (454 aa)
 
   
  0.808
rfaE
Bifunctional protein HldE; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose; In the N-terminal section; belongs to the carbohydrate kinase PfkB family (475 aa)
       
  0.802
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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