STRINGSTRING
GEAM_1606 protein (Ewingella americana) - STRING interaction network
"GEAM_1606" - Cystathionine beta-lyase in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GEAM_1606Cystathionine beta-lyase; Protein involved in pyridoxal phosphate binding and biosynthetic process (395 aa)    
Predicted Functional Partners:
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Protein involved in methionine synthase activity, cobalamin binding, metal ion binding, homocysteine S-methyltransferase activity, zinc ion binding, pteridine-containing compound metabolic process, methionine biosynthetic process and cellular metabolic process (1239 aa)
         
  0.887
GEAM_3777
Aspartokinase/homoserine dehydrogenase; Protein involved in NADP binding, oxidoreductase activity, oxidation-reduction process, cellular amino acid metabolic process and cellular amino acid biosynthetic process (797 aa)
       
  0.781
GEAM_0210
Aspartokinase/homoserine dehydrogenase; Protein involved in NADP binding, oxidoreductase activity, aspartate kinase activity, cellular amino acid biosynthetic process, oxidation-reduction process and cellular amino acid metabolic process (819 aa)
       
  0.781
GEAM_1607
PTS system maltose and glucose-specific IICB components; Protein involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity, sugar-hydrogen symporter activity, biological_process, phosphoenolpyruvate-dependent sugar phosphotransferase system and transport (537 aa)
     
  0.726
GEAM_2726
annotation not available (347 aa)
       
  0.659
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD); Belongs to the LuxS family (171 aa)
         
  0.647
GEAM_0646
Peptidase B; Probably plays an important role in intracellular peptide degradation (436 aa)
     
 
    0.627
pepA
Probable cytosol aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides; Belongs to the peptidase M17 family (503 aa)
     
 
    0.627
pepN
Membrane alanyl aminopeptidase; Protein involved in metallopeptidase activity, zinc ion binding and proteolysis (871 aa)
     
 
    0.627
pepD
Aminoacyl-histidine dipeptidase; Protein involved in hydrolase activity, proteolysis and metabolic process (486 aa)
       
  0.626
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (9%) [HD]