STRINGSTRING
fadR protein (Ewingella americana) - STRING interaction network
"fadR" - Fatty acid metabolism regulator protein in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fadRFatty acid metabolism regulator protein; Multifunctional regulator of fatty acid metabolism (239 aa)    
Predicted Functional Partners:
dsbB
Disulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (176 aa)
 
     
  0.840
fabR
HTH-type transcriptional repressor FabR; Represses the transcription of fabB, involved in unsaturated fatty acid (UFA) biosynthesis. By controlling UFA production, FabR directly influences the physical properties of the membrane bilayer (225 aa)
   
 
 
  0.801
argR
Arginine repressor; Regulates arginine biosynthesis genes (156 aa)
   
     
  0.794
metJ
Met repressor; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family (105 aa)
   
     
  0.786
nhaB
Na(+)/H(+) antiporter NhaB; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons (523 aa)
   
   
  0.775
rraB
Regulator of ribonuclease activity B; Globally modulates RNA abundance by binding to RNase E (Rne) and regulating its endonucleolytic activity. Can modulate Rne action in a substrate-dependent manner by altering the composition of the degradosome (142 aa)
   
          0.750
GEAM_2411
UPF0208 membrane protein GEAM_2411; FIG01056074 (151 aa)
   
        0.740
GEAM_2353
UPF0352 protein GEAM_2353; FIG002927; Belongs to the UPF0352 family (75 aa)
   
          0.728
seqA
Negative modulator of initiation of replication; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated (185 aa)
   
          0.708
GEAM_4049
Lipoprotein NlpI; May be involved in cell division (294 aa)
   
          0.704
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (13%) [HD]