STRINGSTRING
GEAM_1970 protein (Ewingella americana) - STRING interaction network
"GEAM_1970" - Protein TonB in Ewingella americana
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GEAM_1970Protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins (249 aa)    
Predicted Functional Partners:
exbB
MotA/TolQ/ExbB family proton channel protein; Protein involved in protein transporter activity and transport (316 aa)
   
  0.974
btuB
Vitamin B12 transporter BtuB; Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (620 aa)
 
  0.943
GEAM_2313
Protein involved in receptor activity, transporter activity and transport (648 aa)
 
  0.936
GEAM_2637
Protein involved in receptor activity, transporter activity, siderophore transmembrane transporter activity, iron ion binding, (DEPRECATED) siderophore-iron transport, transport and siderophore transport (725 aa)
   
  0.912
tolR
TolR family component of Tol biopolymer transport system; Protein involved in transporter activity, proton transport, (DEPRECATED) cellular membrane organization, transport and protein transport (142 aa)
 
  0.910
tolQ
MotA/TolQ/ExbB family proton channel protein; Protein involved in protein transporter activity, pathogenesis, proton transport, transport and protein transport (229 aa)
   
  0.878
exbD
Protein involved in transporter activity and transport (143 aa)
   
  0.842
GEAM_1248
Protein involved in transporter activity, receptor activity, siderophore transmembrane transporter activity, iron ion binding, (DEPRECATED) siderophore-iron transport, transport and siderophore transport (705 aa)
 
  0.820
feoB
Ferrous iron transport protein B; Probable transporter of a GTP-driven Fe(2+) uptake system (771 aa)
     
   
  0.817
GEAM_2061
TonB-dependent hemin/ferrichrome receptor; Protein involved in transporter activity, receptor activity and transport (694 aa)
   
  0.817
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
Server load: low (13%) [HD]