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purR protein (Ewingella americana) - STRING interaction network
"purR" - HTH-type transcriptional repressor PurR in Ewingella americana
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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purRHTH-type transcriptional repressor PurR; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression (341 aa)    
Predicted Functional Partners:
GEAM_3460
DeoR family glycerol-3-phosphate regulon repressor; Protein involved in sequence-specific DNA binding transcription factor activity and regulation of transcription, DNA-templated (252 aa)
   
 
      0.589
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway (309 aa)
 
  0.582
GEAM_0095
Glutamate synthase [NADPH] large chain; Protein involved in oxidoreductase activity, acting on the CH-NH2 group of donors, glutamate synthase activity, oxidoreductase activity, oxidation-reduction process, glutamate biosynthetic process, nitrogen compound metabolic process and metabolic process (1485 aa)
       
 
  0.521
GEAM_3396
Cyclic AMP receptor protein; Protein involved in sequence-specific DNA binding transcription factor activity and regulation of transcription, DNA-templated (210 aa)
       
 
  0.510
GEAM_2323
PTS system fructose-specific IIA component; Protein involved in sugar-hydrogen symporter activity, transporter activity, phosphoenolpyruvate-dependent sugar phosphotransferase system and transport (376 aa)
     
 
  0.481
GEAM_3143
PTS system fructose-specific IIA component; Protein involved in sugar-hydrogen symporter activity and phosphoenolpyruvate-dependent sugar phosphotransferase system (99 aa)
     
      0.417
GEAM_2527
HPr family PTS system phosphocarrier protein; Protein involved in sugar-hydrogen symporter activity and phosphoenolpyruvate-dependent sugar phosphotransferase system (85 aa)
     
      0.417
GEAM_0067
Nitrogen regulation-associated phosphocarrier protein; Protein involved in sugar-hydrogen symporter activity and phosphoenolpyruvate-dependent sugar phosphotransferase system (90 aa)
     
      0.417
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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