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sufE protein (Ewingella americana) - STRING interaction network
"sufE" - Cysteine desulfuration protein SufE in Ewingella americana
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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sufECysteine desulfuration protein SufE; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family (137 aa)    
Predicted Functional Partners:
sufC
Iron-sulfur cluster assembly ATPase protein; Protein involved in ATPase activity, ATP binding, nucleotide binding, nucleoside-triphosphatase activity, iron-sulfur cluster assembly and transport (248 aa)
 
  0.996
sufD
Protein involved in iron-sulfur cluster assembly (433 aa)
 
  0.996
sufS
Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo (406 aa)
  0.992
sufB
Protein involved in iron-sulfur cluster assembly (507 aa)
 
  0.991
csdA
CsdA family cysteine desulfurase component; Protein involved in cysteine desulfurase activity, iron-sulfur cluster assembly and metabolic process (401 aa)
  0.959
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily (389 aa)
 
 
  0.813
sufA
Protein involved in structural molecule activity, iron-sulfur cluster binding and iron-sulfur cluster assembly; Belongs to the HesB/IscA family (123 aa)
   
   
  0.724
GEAM_2941
CsdL family sulfur transfer protein; Protein involved in catalytic activity (271 aa)
     
 
  0.556
GEAM_3085
Pyridoxal phosphate homeostasis protein; Pyridoxal 5’-phosphate (PLP)-binding protein, which is involved in PLP homeostasis (236 aa)
     
 
    0.523
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily (315 aa)
     
 
  0.503
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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