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sufA protein (Ewingella americana) - STRING interaction network
"sufA" - Protein involved in structural molecule activity, iron-sulfur cluster binding and iron-sulfur cluster assembly in Ewingella americana
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Predicted Interactions
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textmining
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sufAProtein involved in structural molecule activity, iron-sulfur cluster binding and iron-sulfur cluster assembly; Belongs to the HesB/IscA family (123 aa)    
Predicted Functional Partners:
sufB
Protein involved in iron-sulfur cluster assembly (507 aa)
   
 
  0.946
sufC
Iron-sulfur cluster assembly ATPase protein; Protein involved in ATPase activity, ATP binding, nucleotide binding, nucleoside-triphosphatase activity, iron-sulfur cluster assembly and transport (248 aa)
   
 
  0.883
sufD
Protein involved in iron-sulfur cluster assembly (433 aa)
   
 
  0.876
sufS
Cysteine desulfurase; Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under specific conditions such as oxidative stress and iron limitation. Acts as a potent selenocysteine lyase in vitro, that mobilizes selenium from L-selenocysteine. Selenocysteine lyase activity is however unsure in vivo (406 aa)
   
  0.824
iscS
Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily (389 aa)
 
 
  0.803
sufE
Cysteine desulfuration protein SufE; Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process; Belongs to the SufE family (137 aa)
   
   
  0.724
csdA
CsdA family cysteine desulfurase component; Protein involved in cysteine desulfurase activity, iron-sulfur cluster assembly and metabolic process (401 aa)
   
  0.698
GEAM_2032
Glutaredoxin; Protein involved in protein disulfide oxidoreductase activity, electron carrier activity and cell redox homeostasis; Belongs to the glutaredoxin family. Monothiol subfamily (117 aa)
 
  0.668
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (321 aa)
 
   
  0.654
iscR
HTH-type transcriptional regulator IscR; Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins (164 aa)
   
 
  0.651
Your Current Organism:
Ewingella americana
NCBI taxonomy Id: 910964
Other names: E. americana ATCC 33852, Ewingella americana, Ewingella americana ATCC 33852, Ewingella americana ATCC33852, Ewingella americana str. ATCC 33852, Ewingella americana strain ATCC 33852
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