STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NEDD4LE3 ubiquitin-protein ligase NEDD4-like isoform X9. (1264 aa)    
Predicted Functional Partners:
TRAF6
TNF receptor-associated factor 6.
    
 0.927
SMURF2
E3 ubiquitin-protein ligase SMURF2.
    
0.926
SMURF1
E3 ubiquitin-protein ligase SMURF1 isoform X1.
    
0.919
CBL
E3 ubiquitin-protein ligase CBL.
    
 0.917
CBLB
E3 ubiquitin-protein ligase CBL-B isoform X1.
    
 0.917
WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1 isoform X1.
    
0.914
ITCH
E3 ubiquitin-protein ligase Itchy homolog.
    
0.910
MDM2
E3 ubiquitin-protein ligase Mdm2.
    
 0.910
NEDD4
E3 ubiquitin-protein ligase NEDD4 isoform X1.
  
  
 
0.900
SCNN1B
Amiloride-sensitive sodium channel subunit beta.
    
 0.812
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.