STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MC4RMelanocortin 4 receptor. (331 aa)    
Predicted Functional Partners:
POMC
Pro-opiomelanocortin.
    
 0.997
GNAL
Guanine nucleotide-binding protein G(olf) subunit alpha isoform X1.
    
 0.845
AGRP
Agouti related protein.
    
 
 0.835
PIK3R1
Phosphatidylinositol 3-kinase regulatory subunit alpha isoform X1.
    
 0.699
PVALB
Parvalbumin alpha.
    
 0.696
INS
Insulin.
     
 0.696
GPCPD1
Glycerophosphocholine phosphodiesterase GPCPD1 isoform X2.
      
 0.690
RBBP6
E3 ubiquitin-protein ligase RBBP6 isoform X2.
      
 0.690
FST
LOW QUALITY PROTEIN: follistatin.
      
 0.690
RAPGEF2
Rap guanine nucleotide exchange factor 2 isoform X4.
      
 0.690
Your Current Organism:
Serinus canaria
NCBI taxonomy Id: 9135
Other names: Atlantic canary, Canario raza, Common canary, S. canaria, Serinus canarius, canary
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.