EDA protein (Parus major) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EDA

Ectodysplasin-A isoform X1. (240 aa)

Predicted Functional Partners:

EDAR

0.985

EDA2R

0.978

MAP3K7

0.550

MAP3K20

0.550

MAPK9

0.507

MAPK10

0.507

MAPK8

0.507

EDARADD

0.487

NUP214

0.422

DUSP16

0.421

Your Current Organism:

Parus major

NCBI taxonomy Id: 9157
Other names: Great Tit, Kohlmeise, P. major

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DUSP16	EDA	ENSPMJP00000001554	ENSPMJP00000009970	Dual specificity MAP kinase phosphatase.	Ectodysplasin-A isoform X1.	0.421
DUSP16	MAPK10	ENSPMJP00000001554	ENSPMJP00000011441	Dual specificity MAP kinase phosphatase.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.960
DUSP16	MAPK8	ENSPMJP00000001554	ENSPMJP00000021583	Dual specificity MAP kinase phosphatase.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.960
DUSP16	MAPK9	ENSPMJP00000001554	ENSPMJP00000011209	Dual specificity MAP kinase phosphatase.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.954
EDA	DUSP16	ENSPMJP00000009970	ENSPMJP00000001554	Ectodysplasin-A isoform X1.	Dual specificity MAP kinase phosphatase.	0.421
EDA	EDA2R	ENSPMJP00000009970	ENSPMJP00000010069	Ectodysplasin-A isoform X1.	Tumor necrosis factor receptor superfamily member 27.	0.978
EDA	EDAR	ENSPMJP00000009970	ENSPMJP00000015315	Ectodysplasin-A isoform X1.	Tumor necrosis factor receptor superfamily member EDAR isoform X3.	0.985
EDA	EDARADD	ENSPMJP00000009970	ENSPMJP00000004791	Ectodysplasin-A isoform X1.	EDAR associated death domain.	0.487
EDA	MAP3K20	ENSPMJP00000009970	ENSPMJP00000025350	Ectodysplasin-A isoform X1.	Mitogen-activated protein kinase kinase kinase MLT isoform X1.	0.550
EDA	MAP3K7	ENSPMJP00000009970	ENSPMJP00000001792	Ectodysplasin-A isoform X1.	Mitogen-activated protein kinase kinase kinase 7 isoform X1.	0.550
EDA	MAPK10	ENSPMJP00000009970	ENSPMJP00000011441	Ectodysplasin-A isoform X1.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.507
EDA	MAPK8	ENSPMJP00000009970	ENSPMJP00000021583	Ectodysplasin-A isoform X1.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.507
EDA	MAPK9	ENSPMJP00000009970	ENSPMJP00000011209	Ectodysplasin-A isoform X1.	Mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase).	0.507
EDA	NUP214	ENSPMJP00000009970	ENSPMJP00000008386	Ectodysplasin-A isoform X1.	Nuclear pore complex protein Nup214 isoform X1.	0.422
EDA2R	EDA	ENSPMJP00000010069	ENSPMJP00000009970	Tumor necrosis factor receptor superfamily member 27.	Ectodysplasin-A isoform X1.	0.978
EDAR	EDA	ENSPMJP00000015315	ENSPMJP00000009970	Tumor necrosis factor receptor superfamily member EDAR isoform X3.	Ectodysplasin-A isoform X1.	0.985
EDAR	EDARADD	ENSPMJP00000015315	ENSPMJP00000004791	Tumor necrosis factor receptor superfamily member EDAR isoform X3.	EDAR associated death domain.	0.878
EDARADD	EDA	ENSPMJP00000004791	ENSPMJP00000009970	EDAR associated death domain.	Ectodysplasin-A isoform X1.	0.487
EDARADD	EDAR	ENSPMJP00000004791	ENSPMJP00000015315	EDAR associated death domain.	Tumor necrosis factor receptor superfamily member EDAR isoform X3.	0.878
MAP3K20	EDA	ENSPMJP00000025350	ENSPMJP00000009970	Mitogen-activated protein kinase kinase kinase MLT isoform X1.	Ectodysplasin-A isoform X1.	0.550