STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV08_08847Uncharacterized protein. (215 aa)    
Predicted Functional Partners:
PV08_05809
Uncharacterized protein.
   
 0.611
PV08_08850
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
 
 
  0.608
PV08_01228
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
    
  0.557
BNA4
Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.
   
 
  0.546
PV08_07014
Uncharacterized protein.
    
 0.535
PV08_09315
Ubiquitin carboxyl-terminal hydrolase.
    
  0.529
PV08_10384
Mitochondrial-processing peptidase subunit beta; Belongs to the peptidase M16 family.
   
  0.486
PV08_02923
26S proteasome regulatory subunit rpn11.
    
  0.485
PV08_04939
t-SNARE coiled-coil homology domain-containing protein.
    
 0.480
PV08_11246
MHD domain-containing protein; Belongs to the adaptor complexes medium subunit family.
    
  0.471
Your Current Organism:
Exophiala spinifera
NCBI taxonomy Id: 91928
Other names: ATCC 18218, CBS 899.68, DUKE 3342, E. spinifera, NCMH 152, NCPF 2358, Phialophora spinifera, Rhinocladiella spinifera
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.