STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AS28_03612Histone H2A; Belongs to the histone H2A family. (121 aa)    
Predicted Functional Partners:
MYSM1
Histone H2A deubiquitinase MYSM1.
    
 0.951
AS28_12568
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.841
KDM6A
Lysine-specific demethylase 6A.
    
 0.764
AS28_14622
Histone H2A; Belongs to the histone H2A family.
  
0.746
RPS27A
Ubiquitin-40S ribosomal protein S27a.
   
 0.683
POLR2C
DNA-directed RNA polymerase II subunit RPB3.
    
 0.622
GLYR1
Putative oxidoreductase GLYR1.
    
   0.618
PAXIP1
PAX-interacting protein 1.
    
 0.602
POLR2E
DNA-directed RNA polymerases I, II, and III subunit RPABC1.
    
  0.597
LEO1
RNA polymerase-associated protein LEO1.
    
 
 0.596
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.