STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HECTD4Putative E3 ubiquitin-protein ligase HECTD4. (651 aa)    
Predicted Functional Partners:
EVC
Ellis-van Creveld syndrome protein.
   
 0.637
GGA3
ADP-ribosylation factor-binding protein GGA3.
    
 
 0.611
ZFAND4
AN1-type zinc finger protein 4.
    
 0.600
AS28_03099
E3 SUMO-protein ligase RanBP2.
   
 0.521
AS28_03100
Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.
   
 0.521
ACAD10
Acyl-CoA dehydrogenase family member 10.
    
 
 0.499
SLC17A5
Sialin.
    
 
 0.496
AS28_08047
Rab5 GDP/GTP exchange factor.
    
 0.478
NPHP3
Nephrocystin-3.
 
 
 
 0.465
RAN
GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family.
    
 0.442
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.