STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
TGFBR2Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (497 aa)    
Predicted Functional Partners:
TGFBR1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
0.997
TGFB3
Transforming growth factor beta-3.
    
 0.993
TGFB2
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.991
SMURF2
E3 ubiquitin-protein ligase SMURF2.
    
 0.964
ACVRL1
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.
   
0.947
PPP2CB
Serine/threonine-protein phosphatase.
    
 0.912
PPP2CA
Serine/threonine-protein phosphatase.
    
 0.912
SMAD7
Mothers against decapentaplegic 7.
   
 0.788
ACVR1B
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
0.787
ACVR1C
Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily.
   
0.787
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.