STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HMGCLL13-hydroxymethyl-3-methylglutaryl-CoA lyase, cytoplasmic. (307 aa)    
Predicted Functional Partners:
HMGCS1
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
     
 0.960
HMGCS2
3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
     
 0.960
AUH
Uncharacterized protein; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 
 0.959
OXCT1
Uncharacterized protein.
  
 
 0.955
AACS
Acetoacetyl-CoA synthetase.
 
 
 0.949
ACAT1
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.942
ACAT2
Acetyl-CoA acetyltransferase, cytosolic; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.937
ACAA2
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.935
HADHB
Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.935
BDH2
3-hydroxybutyrate dehydrogenase type 2.
   
 
 0.928
Your Current Organism:
Pygoscelis adeliae
NCBI taxonomy Id: 9238
Other names: Adelie penguin, P. adeliae, Pygoscelis adelia
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.