node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
N300_00749 | N300_03475 | A0A091HTQ3 | A0A091IQC3 | Uncharacterized protein. | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | 0.632 |
N300_00749 | N300_05213 | A0A091HTQ3 | A0A091IID7 | Uncharacterized protein. | Breast cancer type 2 susceptibility protein. | 0.598 |
N300_00749 | N300_06977 | A0A091HTQ3 | A0A091IMV8 | Uncharacterized protein. | Exonuclease 1. | 0.801 |
N300_00749 | N300_10658 | A0A091HTQ3 | A0A091HNA5 | Uncharacterized protein. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.974 |
N300_00749 | N300_11166 | A0A091HTQ3 | A0A091HX46 | Uncharacterized protein. | DNA repair protein RAD51 3. | 0.732 |
N300_00749 | N300_11546 | A0A091HTQ3 | A0A091HL99 | Uncharacterized protein. | Meiotic recombination protein DMC1/LIM15; Belongs to the RecA family. | 0.749 |
N300_00749 | N300_13195 | A0A091HTQ3 | A0A091HWY1 | Uncharacterized protein. | Fanconi anemia group M protein. | 0.887 |
N300_00749 | N300_14219 | A0A091HTQ3 | A0A091HKE5 | Uncharacterized protein. | Partner and localizer of BRCA2. | 0.412 |
N300_00749 | N300_15807 | A0A091HTQ3 | A0A091ID70 | Uncharacterized protein. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.716 |
N300_00749 | N300_15827 | A0A091HTQ3 | A0A091J1A9 | Uncharacterized protein. | DNA repair protein XRCC3. | 0.672 |
N300_03475 | N300_00749 | A0A091IQC3 | A0A091HTQ3 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Uncharacterized protein. | 0.632 |
N300_03475 | N300_05213 | A0A091IQC3 | A0A091IID7 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Breast cancer type 2 susceptibility protein. | 0.679 |
N300_03475 | N300_06977 | A0A091IQC3 | A0A091IMV8 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Exonuclease 1. | 0.887 |
N300_03475 | N300_10658 | A0A091IQC3 | A0A091HNA5 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] | 0.986 |
N300_03475 | N300_11166 | A0A091IQC3 | A0A091HX46 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | DNA repair protein RAD51 3. | 0.892 |
N300_03475 | N300_11546 | A0A091IQC3 | A0A091HL99 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Meiotic recombination protein DMC1/LIM15; Belongs to the RecA family. | 0.763 |
N300_03475 | N300_13195 | A0A091IQC3 | A0A091HWY1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Fanconi anemia group M protein. | 0.999 |
N300_03475 | N300_14219 | A0A091IQC3 | A0A091HKE5 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Partner and localizer of BRCA2. | 0.540 |
N300_03475 | N300_15807 | A0A091IQC3 | A0A091ID70 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. | 0.965 |
N300_03475 | N300_15827 | A0A091IQC3 | A0A091J1A9 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. | DNA repair protein XRCC3. | 0.886 |