STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N300_05747DNA ligase. (912 aa)    
Predicted Functional Partners:
N300_15807
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
  
 0.997
N300_03595
X-ray repair cross-complementing protein 5.
   
 0.986
N300_13174
X-ray repair cross-complementing protein 5.
   
 0.985
N300_03561
Non-homologous end-joining factor 1.
    
 0.977
N300_12888
DNA-dependent protein kinase catalytic subunit; Belongs to the PI3/PI4-kinase family.
   
 0.963
N300_06977
Exonuclease 1.
  
 0.903
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
  
 0.902
N300_00481
Protein artemis.
   
 0.902
N300_15799
Meiotic recombination protein REC114-like.
   
 0.902
N300_05759
DNA repair protein complementing XP-G cells.
  
 0.891
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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