STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N300_15693Death-inducer obliterator 1. (2298 aa)    
Predicted Functional Partners:
N300_11720
Set1/Ash2 histone methyltransferase complex subunit ASH2.
   
 
 0.988
N300_03816
Retinoblastoma-binding protein 5.
    
 
 0.981
N300_10271
Histone-lysine N-methyltransferase SETD1B.
   
 
 0.980
N300_06958
Protein dpy-30.
    
 
 0.962
N300_08147
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1.
    
 
 0.849
N300_03241
Actin-like 6A; Belongs to the actin family.
    
 
 0.842
N300_06258
Ubiquitin-40S ribosomal protein S27a.
    
 
 0.842
N300_00616
Histone H2A deubiquitinase MYSM1.
    
 
 0.828
N300_07790
Ubiquitin-60S ribosomal protein L40.
    
   0.818
N300_10970
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
  0.814
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.