STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N300_10224Centrosome-associated protein 350. (3120 aa)    
Predicted Functional Partners:
N300_06927
Serine/threonine-protein kinase SMG1; Belongs to the PI3/PI4-kinase family.
   
  0.846
N300_01927
5'-3' exoribonuclease 1.
   
   0.724
N300_05710
Ubiquitin carboxyl-terminal hydrolase CYLD.
    
 0.717
N300_12751
Transcription factor TFIIIB component B.
   
    0.692
N300_15898
Centrosomal protein of 19 kDa.
    
 
 0.690
N300_07841
PHD finger protein 3.
   
    0.667
N300_03600
Cytochrome P450 27C1; Belongs to the cytochrome P450 family.
    
 0.608
N300_09869
Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]
    
 0.608
N300_15759
Uncharacterized protein; Belongs to the cytochrome P450 family.
    
 0.608
N300_07100
Mitotic checkpoint protein BUB3.
    
 0.605
Your Current Organism:
Calypte anna
NCBI taxonomy Id: 9244
Other names: C. anna
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.