STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ERBB4Receptor protein-tyrosine kinase. (1220 aa)    
Predicted Functional Partners:
NRG1
Neuregulin 1.
    
 0.992
SHC2
Uncharacterized protein.
    
 0.970
PIK3R1
SH2 domain-containing protein.
    
 0.965
BTC
Betacellulin.
    
 0.965
EREG
Epiregulin.
    
 0.962
PIK3R2
Uncharacterized protein.
    
 0.951
PIK3CB
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.944
PIK3R3
Uncharacterized protein.
    
 0.942
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
    
 0.942
PLCG1
Uncharacterized protein.
    
 0.940
Your Current Organism:
Ornithorhynchus anatinus
NCBI taxonomy Id: 9258
Other names: O. anatinus, Platypus anatinus, duck-billed platypus, duckbill platypus, platypus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.