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Oweho_3391 protein (Owenweeksia hongkongensis) - STRING interaction network
"Oweho_3391" - UvrABC system protein A in Owenweeksia hongkongensis
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
Oweho_3391UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (951 aa)    
Predicted Functional Partners:
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (672 aa)
 
 
  0.909
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (927 aa)
 
   
  0.830
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5’ and 3’ sides of the lesion. The N-terminal half is responsible for the 3’ incision and the C-terminal half is responsible for the 5’ incision (601 aa)
 
 
  0.829
Oweho_0767
UvrABC system protein A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (937 aa)
   
   
0.815
Oweho_3390
Cytokinin riboside 5’-monophosphate phosphoribohydrolase; PFAM- Possible lysine decarboxylase; TIGRFAM- TIGR00725 family protein; TIGR00730 family protein; Belongs to the LOG family (241 aa)
              0.771
Oweho_3052
PFAM- UvrD/REP helicase; TIGRFAM- ATP-dependent DNA helicase PcrA (792 aa)
 
 
  0.678
mfd
Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site (1121 aa)
 
 
  0.656
Oweho_3392
Soluble lytic murein transglycosylase-like protein; PFAM- Transglycosylase SLT domain (339 aa)
              0.639
Oweho_0401
PFAM- Exonuclease; GIY-YIG catalytic domain; TIGRFAM- exonuclease, DNA polymerase III, epsilon subunit family (441 aa)
   
 
  0.618
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (382 aa)
   
 
  0.608
Your Current Organism:
Owenweeksia hongkongensis
NCBI taxonomy Id: 926562
Other names: O. hongkongensis DSM 17368, Owenweeksia hongkongensis, Owenweeksia hongkongensis DSM 17368, Owenweeksia hongkongensis DSM17368
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