STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
AFK04934.1acetate/CoA ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; TIGRFAM: acetate--CoA ligase; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR011904:IPR000873; KEGG: sli:Slin_2894 acetate/CoA ligase; PFAM: AMP-dependent synthetase/ligase; SPTR: Acetyl-coenzyme A synthetase; TIGRFAM: Acetate--CoA ligase. (633 aa)    
Predicted Functional Partners:
AFK04457.1
PFAM: Citrate synthase; TIGRFAM: citrate synthase I (hexameric type); COGs: COG0372 Citrate synthase; InterPro IPR002020:IPR010953; KEGG: dfe:Dfer_0554 citrate synthase I; PFAM: Citrate synthase-like; SPTR: Citrate synthase; TIGRFAM: Citrate synthase, type II.
  
 0.975
AFK01788.1
PFAM: Malate synthase; TIGRFAM: malate synthase A; COGs: COG2225 Malate synthase; InterPro IPR011076:IPR006252; KEGG: tro:trd_0495 malate synthase; PFAM: Malate synthase-like, core; SPTR: Malate synthase; TIGRFAM: Malate synthase A.
   
 0.963
AFK04932.1
AMP-dependent synthetase and ligase; PFAM: Domain of unknown function (DUF3448); AMP-binding enzyme; COGs: COG0365 Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase; InterPro IPR000873; KEGG: hmg:100198705 similar to acyl-CoA synthetase short-chain family member 3; PFAM: AMP-dependent synthetase/ligase; SPTR: AMP-dependent synthetase and ligase.
 
  
 
0.955
AFK01894.1
PFAM: Enoyl-CoA hydratase/isomerase family; 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; COGs: COG1250 3-hydroxyacyl-CoA dehydrogenase; InterPro IPR001753:IPR006176:IPR006108; KEGG: sli:Slin_6109 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein; PFAM: 3-hydroxyacyl-CoA dehydrogenase, NAD binding; Crotonase, core; 3-hydroxyacyl-CoA dehydrogenase, C-terminal; SPTR: 3-hydroxyacyl-CoA dehydrogenase NAD-binding protein.
 
 0.953
AFK03519.1
2-oxoacid:acceptor oxidoreductase, alpha subunit; PFAM: domain; Pyruvate ferredoxin/flavodoxin oxidoreductase; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit; COGs: COG0674 Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductase alpha subunit; InterPro IPR019752:IPR002880; KEGG: 2-oxoacid:acceptor oxidoreductase subunit alpha; PFAM: Pyruvate flavodoxin/ferredoxin oxidoreductase, N-terminal; Pyruvate/ketoisovalerate oxidoreductase; SPTR: 2-ketoglutarate: nadp oxidoreductase, alpha subunit; TIGRFAM: 2-oxoacid:acceptor oxidoreductase, alpha subunit.
  
 
 0.941
AFK02493.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: sli:Slin_6110 acetyl-CoA acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase.
  
 
 0.936
AFK05246.1
acetyl-CoA acetyltransferase; PFAM: Thiolase, C-terminal domain; Thiolase, N-terminal domain; TIGRFAM: acetyl-CoA acetyltransferases; COGs: COG0183 Acetyl-CoA acetyltransferase; InterPro IPR002155; KEGG: dfe:Dfer_2430 acetyl-CoA acetyltransferase; SPTR: Acetyl-CoA acetyltransferase; TIGRFAM: Thiolase.
  
 
 0.936
AFK03852.1
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: dfe:Dfer_0072 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde dehydrogenase.
  
 0.931
AFK04777.1
PFAM: Aldehyde dehydrogenase family; COGs: COG1012 NAD-dependent aldehyde dehydrogenase; InterPro IPR015590; KEGG: cpi:Cpin_3681 aldehyde dehydrogenase; PFAM: Aldehyde dehydrogenase; SPTR: Aldehyde Dehydrogenase.
  
 0.931
AFK02895.1
Pyruvate carboxyltransferase; PFAM: HMGL-like; COGs: COG0119 Isopropylmalate/homocitrate/citramalate synthase; InterPro IPR000891; KEGG: lby:Lbys_2027 2-isopropylmalate synthase; PFAM: Pyruvate carboxyltransferase; SPTR: 2-isopropylmalate synthase.
  
 
 0.919
Your Current Organism:
Emticicia oligotrophica
NCBI taxonomy Id: 929562
Other names: E. oligotrophica DSM 17448, Emticicia oligotrophica DSM 17448, Emticicia oligotrophica GPTSA100-15, Emticicia oligotrophica str. DSM 17448, Emticicia oligotrophica strain DSM 17448
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