node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KCTD2 | NFATC2IP | ENSSHAP00000022093 | ENSSHAP00000014750 | Potassium channel tetramerization domain containing 2. | Ubiquitin-like domain-containing protein. | 0.814 |
KCTD2 | SAE1 | ENSSHAP00000022093 | ENSSHAP00000003186 | Potassium channel tetramerization domain containing 2. | SUMO1 activating enzyme subunit 1. | 0.930 |
KCTD2 | SUMO1 | ENSSHAP00000022093 | ENSSHAP00000013993 | Potassium channel tetramerization domain containing 2. | Small ubiquitin-related modifier. | 0.932 |
KCTD2 | SUMO3 | ENSSHAP00000022093 | ENSSHAP00000002507 | Potassium channel tetramerization domain containing 2. | Small ubiquitin-related modifier. | 0.949 |
KCTD2 | UBA2 | ENSSHAP00000022093 | ENSSHAP00000002779 | Potassium channel tetramerization domain containing 2. | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | 0.945 |
KCTD2 | UBE2V1 | ENSSHAP00000022093 | ENSSHAP00000011776 | Potassium channel tetramerization domain containing 2. | Ubiquitin conjugating enzyme E2 V1. | 0.923 |
MOCS2 | SAE1 | ENSSHAP00000003045 | ENSSHAP00000003186 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | SUMO1 activating enzyme subunit 1. | 0.717 |
MOCS2 | UBA2 | ENSSHAP00000003045 | ENSSHAP00000002779 | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | 0.717 |
NFATC2IP | KCTD2 | ENSSHAP00000014750 | ENSSHAP00000022093 | Ubiquitin-like domain-containing protein. | Potassium channel tetramerization domain containing 2. | 0.814 |
NFATC2IP | SAE1 | ENSSHAP00000014750 | ENSSHAP00000003186 | Ubiquitin-like domain-containing protein. | SUMO1 activating enzyme subunit 1. | 0.908 |
NFATC2IP | UBA2 | ENSSHAP00000014750 | ENSSHAP00000002779 | Ubiquitin-like domain-containing protein. | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | 0.897 |
NFATC2IP | UBE2I | ENSSHAP00000014750 | ENSSHAP00000008109 | Ubiquitin-like domain-containing protein. | Ubiquitin conjugating enzyme E2 I. | 0.830 |
NFATC2IP | UBE2V1 | ENSSHAP00000014750 | ENSSHAP00000011776 | Ubiquitin-like domain-containing protein. | Ubiquitin conjugating enzyme E2 V1. | 0.592 |
SAE1 | KCTD2 | ENSSHAP00000003186 | ENSSHAP00000022093 | SUMO1 activating enzyme subunit 1. | Potassium channel tetramerization domain containing 2. | 0.930 |
SAE1 | MOCS2 | ENSSHAP00000003186 | ENSSHAP00000003045 | SUMO1 activating enzyme subunit 1. | Molybdopterin synthase catalytic subunit; Catalytic subunit of the molybdopterin synthase complex, a complex that catalyzes the conversion of precursor Z into molybdopterin. Acts by mediating the incorporation of 2 sulfur atoms from thiocarboxylated MOCS2A into precursor Z to generate a dithiolene group; Belongs to the MoaE family. MOCS2B subfamily. | 0.717 |
SAE1 | NFATC2IP | ENSSHAP00000003186 | ENSSHAP00000014750 | SUMO1 activating enzyme subunit 1. | Ubiquitin-like domain-containing protein. | 0.908 |
SAE1 | SUMO1 | ENSSHAP00000003186 | ENSSHAP00000013993 | SUMO1 activating enzyme subunit 1. | Small ubiquitin-related modifier. | 0.984 |
SAE1 | SUMO3 | ENSSHAP00000003186 | ENSSHAP00000002507 | SUMO1 activating enzyme subunit 1. | Small ubiquitin-related modifier. | 0.980 |
SAE1 | UBA2 | ENSSHAP00000003186 | ENSSHAP00000002779 | SUMO1 activating enzyme subunit 1. | SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. | 0.997 |
SAE1 | UBE2F | ENSSHAP00000003186 | ENSSHAP00000006138 | SUMO1 activating enzyme subunit 1. | UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. | 0.607 |