STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RNF40E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1014 aa)    
Predicted Functional Partners:
RNF20
E3 ubiquitin protein ligase; Belongs to the BRE1 family.
  
0.969
LEO1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.960
UBE2B-2
UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family.
   
 0.847
UBE2B
UBIQUITIN_CONJUGAT_2 domain-containing protein.
   
 0.847
WAC
WW domain containing adaptor with coiled-coil.
   
 0.811
CDC73
Cell division cycle 73.
   
 0.775
PAF1
Uncharacterized protein.
    
 0.755
TRIP12
Thyroid hormone receptor interactor 12.
   
  
 0.729
CTR9
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.718
SETD2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.711
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.