STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RFX1Regulatory factor X1. (963 aa)    
Predicted Functional Partners:
FOXJ2
Forkhead box J2.
    
 
 0.715
ATR
ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family.
    
 
 0.701
RFXAP
RFXA_RFXANK_bdg domain-containing protein.
    
 
 0.700
PAX6
Paired box 6.
      
 0.694
NF1
Neurofibromin 1.
      
 0.694
CREB1
cAMP responsive element binding protein 1.
   
 
 0.674
RFXANK
Regulatory factor X associated ankyrin containing protein.
   
 
 0.669
CIITA
NACHT domain-containing protein.
    
 
 0.603
CHEK2
Checkpoint kinase 2.
   
 
 0.572
NFIC
Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication.
    
 
 0.561
Your Current Organism:
Sarcophilus harrisii
NCBI taxonomy Id: 9305
Other names: S. harrisii, Sarcophilus laniarius, Tasmanian devil
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